Literature DB >> 4020383

Subcellular distribution of glutamic acid decarboxylase in rat brain regions following electroconvulsive stimulation.

A Stelzer, R Laas, A Fleissner.   

Abstract

Electroconvulsive stimulation of rats evoked significant increases of glutamic acid decarboxylase (GAD) activity in the synaptosomal fractions of neocortex (including white matter) and hippocampal formation. The elevation of synaptosomal-bound GAD activity was not significant in cingulate cortex, striatum, caudal brainstem and thalamus. The electroconvulsive shocks had no effect on the GAD activity of the cytoplasmic fractions of any brain regions investigated. The highest physiological level of synaptosomal GAD activity was found in thalamus, followed (in decreasing order) by striatum, hippocampus, cingulate cortex, caudal brainstem and neocortex.

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Year:  1985        PMID： 4020383     DOI： 10.1007/bf01260419

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  13 in total

1.  Evidence for a role of glutamate decarboxylase activity as a regulatory mechanism of cerebral excitability.

Authors:  R Tapia; M E Sandoval; P Contreras
Journal:  J Neurochem       Date:  1975-06       Impact factor: 5.372

2.  SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND GAMMA-AMINOBUTYRIC ACID CYCLES IN RAT BRAIN.

Authors:  L SALGANICOFF; E DEROBERTIS
Journal:  J Neurochem       Date:  1965-04       Impact factor: 5.372

3.  Presynaptic calcium currents and their relation to synaptic transmission: voltage clamp study in squid giant synapse and theoretical model for the calcium gate.

Authors:  R Llinás; I Z Steinberg; K Walton
Journal:  Proc Natl Acad Sci U S A       Date:  1976-08       Impact factor: 11.205

4.  Effects of depolarization on cofactor regulation of glutamic acid decarboxylase in substantia nigra synaptosomes.

Authors:  L P Miller; J R Walters
Journal:  J Neurochem       Date:  1979-08       Impact factor: 5.372

5.  Membrane affinities and subcellular distribution of the different molecular forms of choline acetyltransferase from rat.

Authors:  F Fonnum; D Malthe-Sorenssen
Journal:  J Neurochem       Date:  1973-05       Impact factor: 5.372

6.  Tryptophan-5-hydroxylase: function and control.

Authors:  E M Gál
Journal:  Adv Biochem Psychopharmacol       Date:  1974

7.  Choline acetyltransferase binding to and release from membranes.

Authors:  F Fonnum
Journal:  Biochem J       Date:  1968-09       Impact factor: 3.857

8.  Brain glutamate decarboxylase: properties of its calcium-dependent binding to liposomes and kinetics of the bound and the free enzyme.

Authors:  M Covarrubias; R Tapia
Journal:  J Neurochem       Date:  1980-06       Impact factor: 5.372

9.  Calcium-dependent binding of brain glutamate decarboxylase to phospholipid vesicles.

Authors:  M Covarrubias; R Tapia
Journal:  J Neurochem       Date:  1978-11       Impact factor: 5.372

10.  Studies on the uptake of [3H]dopamine by synaptic vesicle fraction isolated from bovine brain.

Authors:  T Tsudzuki
Journal:  J Biochem       Date:  1981-01       Impact factor: 3.387
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  2 in total

Review 1.  Regulatory properties of brain glutamate decarboxylase.

Authors:  D L Martin
Journal:  Cell Mol Neurobiol       Date:  1987-09       Impact factor: 5.046

2.  A membrane form of brain L-glutamate decarboxylase: identification, isolation, and its relation to insulin-dependent mellitus.

Authors:  B Nathan; J Bao; C C Hsu; P Aguilar; R Wu; M Yarom; C Y Kuo; J Y Wu
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-04       Impact factor: 11.205
  2 in total

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