Literature DB >> 4019307

Aridicins, novel glycopeptide antibiotics. I. Taxonomy, production and biological activity.

M C Shearer, P Actor, B A Bowie, S F Grappel, C H Nash, D J Newman, Y K Oh, C H Pan, L J Nisbet.   

Abstract

A new species of a new genus of the Actinomycetales was discovered, Kibdelosporangium aridum. This strain produces a new family of glycopeptide antibiotics designated aridicins, that contain an unusual glycolipid constituent. They inhibit Gram-positive bacteria, including staphylococci, enterococci and Clostridium sp.

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Year:  1985        PMID: 4019307     DOI: 10.7164/antibiotics.38.555

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  3 in total

1.  Protein binding of glycopeptide antibiotics with diverse physical-chemical properties in mouse, rat, and human serum.

Authors:  R W Wittendorf; J E Swagzdis; R Gifford; B A Mico
Journal:  J Pharmacokinet Biopharm       Date:  1987-02

2.  Antimicrobial activity of aridicins, novel glycopeptide antibiotics with high and prolonged levels in blood.

Authors:  S F Grappel; A J Giovenella; L Phillips; D H Pitkin; L J Nisbet
Journal:  Antimicrob Agents Chemother       Date:  1985-11       Impact factor: 5.191

3.  Charge and lipophilicity govern the pharmacokinetics of glycopeptide antibiotics.

Authors:  D H Pitkin; B A Mico; R D Sitrin; L J Nisbet
Journal:  Antimicrob Agents Chemother       Date:  1986-03       Impact factor: 5.191

  3 in total

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