Literature DB >> 4018230

Acetylcholine induced endothelial-dependent vasodilation increases as artery diameter decreases in the rabbit ear.

M P Owen, J A Bevan.   

Abstract

Isolated resistance vessels in the rabbit ear preconstricted with histamine were relaxed by acetylcholine by a proportionately greater amount than the central ear artery. The relaxation was antagonized by atropine and also by endothelium removal. Our studies represent the first direct evidence that endothelium-dependent dilation can occur in resistance vessels.

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Year:  1985        PMID： 4018230     DOI： 10.1007/bf01952142

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  4 in total

1.  Mechanical properties of vascular smooth muscle cells in situ.

Authors:  M J Mulvany; W Halpern
Journal:  Nature       Date:  1976-04-15       Impact factor: 49.962

2.  A direct method for recording tension changes in the wall of small blood vessels in vitro.

Authors:  J A Bevan; J V Osher
Journal:  Agents Actions       Date:  1972

3.  The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine.

Authors:  R F Furchgott; J V Zawadzki
Journal:  Nature       Date:  1980-11-27       Impact factor: 49.962

4.  Adrenergic control in three artery segments of diminishing diameter in rabbit ear.

Authors:  M P Owen; J G Walmsley; M F Mason; R D Bevan; J A Bevan
Journal:  Am J Physiol       Date:  1983-08
  4 in total
  7 in total

1.  X-irradiation attenuates relaxant responses in the rabbit ear artery.

Authors:  K I Maynard; A L Stewart-Lee; P Milner; G Burnstock
Journal:  Br J Pharmacol       Date:  1992-01       Impact factor: 8.739

2.  EDRF-mediated dilatation in the rat isolated perfused kidney: a microangiographic study.

Authors:  G A Burton; T M Griffith; D H Edwards
Journal:  Br J Pharmacol       Date:  1989-12       Impact factor: 8.739

3.  Endothelium-derived relaxing factor (EDRF) and resistance vessels in an intact vascular bed: a microangiographic study of the rabbit isolated ear.

Authors:  T M Griffith; D H Edwards; R L Davies; T J Harrison; K T Evans
Journal:  Br J Pharmacol       Date:  1988-03       Impact factor: 8.739

Review 4.  Vascular endothelium in ischemic heart disease: possible role for endothelium-derived relaxing factor.

Authors:  A H Henderson
Journal:  Cardiovasc Drugs Ther       Date:  1989-06       Impact factor: 3.727

5.  Endothelium-dependent modulation of resistance vessel contraction: studies with NG-nitro-L-arginine methyl ester and NG-nitro-L-arginine.

Authors:  M A Bennett; P A Watt; H Thurston
Journal:  Br J Pharmacol       Date:  1992-10       Impact factor: 8.739

6.  Impaired cholinergic vasodilation in the cholesterol-fed rabbit in vivo.

Authors:  C Bossaller; H Yamamoto; P R Lichtlen; P D Henry
Journal:  Basic Res Cardiol       Date:  1987 Jul-Aug       Impact factor: 17.165

7.  Effects of basal and acetylcholine-induced release of endothelium-derived relaxing factor on contraction to alpha-adrenoceptor agonists in a rabbit artery and corresponding veins.

Authors:  J C McGrath; S Monaghan; A G Templeton; V G Wilson
Journal:  Br J Pharmacol       Date:  1990-01       Impact factor: 8.739
  7 in total

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