| Literature DB >> 4018123 |
Abstract
The effect of angiotensin II (AII) on calcium exchanges in isolated rat aorta was investigated using the 45Ca lanthanum technique. AII induced a rapid (10 s) and long-lasting (120 min) increase of calcium uptake and enhanced calcium release for a short period. AII-stimulated calcium uptake was antagonized by saralasin and verapamil but not by indomethacin. These data indicate that AII increases rat aortic calcium exchanges via receptor-operated and voltage-dependent calcium channels.Entities:
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Year: 1985 PMID： 4018123 DOI： 10.1016/0014-2999(85)90122-0
Source DB: PubMed Journal: Eur J Pharmacol ISSN： 0014-2999 Impact factor: 4.432