Literature DB >> 4016798

Phase II trial of elliptinium in advanced renal cell carcinoma.

P Caillé, J M Mondesir, J P Droz, P Kerbrat, A Goodman, J P Ducret, C Theodore, M Spielman, J Rouëssé, J L Amiel.   

Abstract

Forty patients with advanced renal cell carcinoma were treated with elliptinium by a weekly infusion of 100 mg/m2. Of 38 evaluable patients, five had an objective response (13.2%). Average response duration was 8 months (range, 5-11). The major dose-limiting toxic effect was induction of antielliptinium antibodies, with the risk of intravascular hemolysis. Elliptinium has modest activity in advanced renal cell cancer and does not produce myelosuppression.

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Year:  1985        PMID: 4016798

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN: 0361-5960


  3 in total

1.  Activity of batracylin (NSC-320846) against solid tumors of mice.

Authors:  P Mucci-LoRusso; L Polin; M C Bissery; F Valeriote; J Plowman; G D Luk; T H Corbett
Journal:  Invest New Drugs       Date:  1989-11       Impact factor: 3.850

Review 2.  Hypersensitivity reactions from antineoplastic agents.

Authors:  R B Weiss; J R Baker
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

Review 3.  Target identification of natural medicine with chemical proteomics approach: probe synthesis, target fishing and protein identification.

Authors:  Xiao Chen; Yutong Wang; Nan Ma; Jing Tian; Yurou Shao; Bo Zhu; Yin Kwan Wong; Zhen Liang; Chang Zou; Jigang Wang
Journal:  Signal Transduct Target Ther       Date:  2020-05-21
  3 in total

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