Literature DB >> 4016150

Reduction of 7-ketolithocholic acid to chenodeoxycholic acid by rat liver preparations in vitro.

Y Amuro, W Yamade, T Nakano, E Hayashi, T Hada, K Higashino.   

Abstract

The formation of chenodeoxycholic acid via 7-ketolithocholic acid by rat liver preparations was examined in vitro. Results showed that a rat liver preparation reduced 7-ketolithocholic acid mainly to chenodeoxycholic acid and to ursodeoxycholic acid in a smaller amount, and that the reductase required NADPH but not NADH as coenzyme and was mainly localized in the microsomes.

Entities:  

Mesh:

Substances:

Year:  1985        PMID: 4016150     DOI: 10.1016/0304-4165(85)90026-1

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  2 in total

1.  Hepatic biotransformation and choleretic effect of 7-ketolithocholic acid in the rat.

Authors:  S Kanai; Y Sato; M Nokubo; K Kitani
Journal:  Lipids       Date:  1989-10       Impact factor: 1.880

2.  Identification and characterization of dehydrocholic acid reductase system in the cytosol of human red blood cells.

Authors:  M Tani; J Goto; I Makino
Journal:  J Gastroenterol       Date:  1994-10       Impact factor: 7.527

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.