Literature DB >> 401543

Insulin, glucagon, and glucose exhibit synchronous, sustained oscillations in fasting monkeys.

C J Goodner, B C Walike, D J Koerker, J W Ensinck, A C Brown, E W Chideckel, J Palmer, L Kalnasy.   

Abstract

In overnight fasted rhesus monkeys, synchronous, regular oscillations occurred in the plasma concentrations of glucose, insulin, and glucagon. The oscillations displayed a period averaging 9 minutes. The amplitudes for insulin and glucagon were ten and five times greater than for glucose. Insulin cycled in and glucagon out of phase with glucose. In baboons, oscillations of glucose and insulin were smaller than in rhesus monkeys, while in man, regular oscillations were not observed.

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Year:  1977        PMID: 401543     DOI: 10.1126/science.401543

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  41 in total

1.  Rapid oscillations in omental lipolysis are independent of changing insulin levels in vivo.

Authors:  L Getty; A E Panteleon; S D Mittelman; M K Dea; R N Bergman
Journal:  J Clin Invest       Date:  2000-08       Impact factor: 14.808

2.  Loss of regular oscillatory insulin secretion in islet cell antibody positive non-diabetic subjects.

Authors:  P J Bingley; D R Matthews; A J Williams; G F Bottazzo; E A Gale
Journal:  Diabetologia       Date:  1992-01       Impact factor: 10.122

3.  Paracrine regulation of glucagon secretion: the β/α/δ model.

Authors:  Margaret Watts; Joon Ha; Ofer Kimchi; Arthur Sherman
Journal:  Am J Physiol Endocrinol Metab       Date:  2016-02-02       Impact factor: 4.310

Review 4.  Complex systems model of fatigue: integrative homoeostatic control of peripheral physiological systems during exercise in humans.

Authors:  E V Lambert; A St Clair Gibson; T D Noakes
Journal:  Br J Sports Med       Date:  2005-01       Impact factor: 13.800

Review 5.  The impact of hormone physiology on clinical practice with reference to two papers spanning 40 years of endocrinology.

Authors:  P C Hindmarsh
Journal:  Arch Dis Child       Date:  2005-11       Impact factor: 3.791

6.  Low- and high-frequency insulin secretion pulses in normal subjects and pancreas transplant recipients: role of extrinsic innervation.

Authors:  G E Sonnenberg; R G Hoffmann; C P Johnson; A H Kissebah
Journal:  J Clin Invest       Date:  1992-08       Impact factor: 14.808

7.  Long lasting synchronization of calcium oscillations by cholinergic stimulation in isolated pancreatic islets.

Authors:  Min Zhang; Bernard Fendler; Bradford Peercy; Pranay Goel; Richard Bertram; Arthur Sherman; Leslie Satin
Journal:  Biophys J       Date:  2008-08-15       Impact factor: 4.033

8.  Glucose modulates [Ca2+]i oscillations in pancreatic islets via ionic and glycolytic mechanisms.

Authors:  Craig S Nunemaker; Richard Bertram; Arthur Sherman; Krasimira Tsaneva-Atanasova; Camille R Daniel; Leslie S Satin
Journal:  Biophys J       Date:  2006-06-30       Impact factor: 4.033

9.  Serum insulin aspart concentrations following high-dose insulin aspart administered directly into the duodenum of healthy subjects: an open-labeled, single-blinded, and uncontrolled exploratory trial.

Authors:  Charlotte A Ihlo; Karin Bak Aksglaede; Torben Laursen; Torsten Lauritzen; Jens Sandahl Christiansen
Journal:  J Diabetes Sci Technol       Date:  2009-09-01

10.  Cytoplasmic Ca2+ in glucagon-producing pancreatic alpha-cells exposed to carbachol and agents affecting Na+ fluxes.

Authors:  A Berts; E Gylfe; B Hellman
Journal:  Endocrine       Date:  1997-02       Impact factor: 3.633

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