Literature DB >> 4013920

Reaction of pig plasma benzylamine oxidase with beta-aminopropionitrile.

L Raimondi, G Banchelli, B Bertocci, M Lodovici, G Ignesti, R Pirisino, F Buffoni, V Bertini, A De Munno.   

Abstract

Beta-aminopropionitrile (BAPN) is an inhibitor of pig plasma benzylamine oxidase. BAPN is oxidized by benzylamine oxidase. Inhibition develops in a time-dependent fashion upon incubation of BAPN with the enzyme in the absence of substrate. The product of oxidation of BAPN by benzylamine oxidase, cyanacetaldehyde, was identified and prepared by synthesis. It is an irreversible inhibitor of the enzyme.

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Year:  1985        PMID： 4013920     DOI： 10.1007/bf01983110

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  8 in total

1.  BENZYLAMINE OXIDASE AND HISTAMINASE: PURIFICATION AND CRYSTALLIZATION OF AN ENZYME FROM PIG PLASMA.

Authors:  F BUFFONI; H BLASCHKO
Journal:  Proc R Soc Lond B Biol Sci       Date:  1964-12-15

2.  Nonpeptidyl amine inhibitors are substrates of lysyl oxidase.

Authors:  P C Trackman; H M Kagan
Journal:  J Biol Chem       Date:  1979-08-25       Impact factor: 5.157

3.  Comparison of the 14-C-putrescine assay with the NADH test for the determination of diamine oxidase: description of a standard procedure with a high precision and an improved accuracy.

Authors:  J Kusche; H Richter; R Hesterberg; J Schmidt; W Lorenz
Journal:  Agents Actions       Date:  1973-10

4.  Standardization of serum ceruloplasmin concentrations in international enzyme units with o-dianisidine dihydrochloride as substrate.

Authors:  H P Lehmann; K H Schosinsky; M F Beeler
Journal:  Clin Chem       Date:  1974-12       Impact factor: 8.327

5.  The cross-linking of collagen and elastin: enzymatic conversion of lysine in peptide linkage to alpha-aminoadipic-delta-semialdehyde (allysine) by an extract from bone.

Authors:  S R Pinnell; G R Martin
Journal:  Proc Natl Acad Sci U S A       Date:  1968-10       Impact factor: 11.205

6.  Interaction of the lathyrogen beta-aminopropionitrile (BAPN) with a copper-containing amine oxidase.

Authors:  R C Page; E P Benditt
Journal:  Proc Soc Exp Biol Med       Date:  1967-02

7.  Active-sitve titration of pig plasma benzylamine oxidase with phenylhydrazine.

Authors:  F Buffoni; G Ignesti
Journal:  Biochem J       Date:  1975-02       Impact factor: 3.857

8.  Reaction of aortic lysyl oxidase with beta-aminopropionitrile.

Authors:  S S Tang; P C Trackman; H M Kagan
Journal:  J Biol Chem       Date:  1983-04-10       Impact factor: 5.157
  8 in total

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