Literature DB >> 4011650

Effect of clonidine on stress-induced cortisol release in man during surgery.

A Masala, G Satta, S Alagna, V Anania, G A Frassetto, P P Rovasio, A Semiani.   

Abstract

The effect of clonidine on stress-induced cortisol secretion was studied in 10 patients undergoing general anesthesia for surgery; six other patients served as a control group and none of them was given clonidine. Central and peripheral alpha 2 stimulation by clonidine (average dose:0.45 mg over 60 minutes) was able to completely suppress cortisol release during surgery.

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Year:  1985        PMID： 4011650     DOI： 10.1016/0031-6989(85)90104-3

Source DB:  PubMed          Journal:  Pharmacol Res Commun        ISSN： 0031-6989


  3 in total

Review 1.  Perioperative glucocorticoid coverage. A reassessment 42 years after emergence of a problem.

Authors:  M Salem; R E Tainsh; J Bromberg; D L Loriaux; B Chernow
Journal:  Ann Surg       Date:  1994-04       Impact factor: 12.969

2.  Effects of intravenous clonidine on haemodynamics and on plasma cortisol level during laparoscopic cholecystectomies.

Authors:  Hiremathada Sahajananda; Sudheer Rao
Journal:  Indian J Anaesth       Date:  2015-01

3.  Impact of Adrenal Function on Hemostasis/Endothelial Function in Patients Undergoing Surgery.

Authors:  Stefan Fischli; Viktor von Wyl; Walter Wuillemin; Roland von Känel; Philipp Schütz; Mirjam Christ-Crain; Fabian Studer; Lukas Brander; Guido Schüpfer; Jürg Metzger; Christoph Henzen
Journal:  J Endocr Soc       Date:  2021-03-23
  3 in total

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