New steps in the intra-arterial chemotherapy of head and neck tumors.

Regional and general chemotherapy were employed in more than 370 cases. Various examinations (patent blue staining, eye fundus, xeroangiography and angioscintigraphy) were carried out in an effort to understand and explain the successes or failures of regional chemotherapy. Intra-arterial chemotherapy is recommended for preoperative, postoperative and palliative purposes, mainly for tumors situated in the parotid, maxillary, retromaxillary and soft palatal regions. It is not recommended in cases of radically operable carcinomas of the tongue, floor of the mouth and lip.