Theiler's virus encephalomyelitis is unaffected by treatment with myelin components.

Treatment of SJL/J mice with myelin components prior to infection with Theiler's picornavirus did not effect the development of inflammatory demyelinating lesions characteristic of Theiler's mouse encephalomyelitis. These results suggest that the pathogenesis of this disease differs from experimental autoimmune encephalomyelitis, which can be suppressed by such a treatment.