| Literature DB >> 4008328 |
A Endo, H Yamashita, H Naoki, T Iwashita, Y Mizukawa.
Abstract
Several fungal strains were found to convert compactin (ML-236B) to 5'-phosphocompactic acid. The product was isolated by solvent extraction and column chromatography, and identified by IR, UV, 1H NMR, 13C NMR and 31P NMR spectroscopy. Related structures (monacolin K, L and X) were also transformed to their corresponding phosphorylated analogues. The products were re-converted back to respective parental compounds by treatment with alkaline phosphatase of calf intestine.Entities:
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Year: 1985 PMID: 4008328 DOI: 10.7164/antibiotics.38.328
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN: 0021-8820 Impact factor: 2.649