Literature DB >> 400827

Mode of action of the Haemophilus bactericidal factor.

R G Streker, R A Venezia, R G Robertson.   

Abstract

Haemocin, a bacteriocin produced by Haemophilus influenzae b, caused pronounced cell elongation of the sensitive strains H. influenzae Rd and Escherichia coli CR34 thyA. In the sensitive strains, haemocin markedly inhibited the synthesis of deoxyribonucleic acid (DNA) but did not affect either ribonucleic acid or protein synthesis. The observed inhibition in synthesis of DNA was not due to degradation of preexisting DNA. The data suggest that haemocin may specifically inhibit DNA synthesis.

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Year:  1978        PMID： 400827      PMCID： PMC352275          DOI： 10.1128/AAC.13.3.527

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  8 in total

1.  MECHANISM OF ACTION OF COLICINES.

Authors:  M NOMURA
Journal:  Proc Natl Acad Sci U S A       Date:  1964-12       Impact factor: 11.205

2.  POSSIBLE SYNTHESIS OF POLYRIBONUCLEOTIDES OF KNOWN BASE-TRIPLET SEQUENCES.

Authors:  R W MASTER
Journal:  Nature       Date:  1965-04-03       Impact factor: 49.962

3.  [Biosynthesis of a colicin and its mode of action].

Authors:  F JACOB; L SIMINOVITCH; E WOLLMAN
Journal:  Ann Inst Pasteur (Paris)       Date:  1952-09

4.  Bactericidal factor produced by Haemophilus influenzae b: partial purification of the factor and transfer of its genetic determinant.

Authors:  R A Venezia; P M Matusiak; R G Robertson
Journal:  Antimicrob Agents Chemother       Date:  1977-04       Impact factor: 5.191

5.  Colicin E3-directed changes in ribosome function and polyribosome metabolism in Escherichia coli K12.

Authors:  B W Senior; J Kwasniak; I B Holland
Journal:  J Mol Biol       Date:  1970-10-28       Impact factor: 5.469

6.  Mode of action of colicins of types E1, E2, E3, and K.

Authors:  P Reeves
Journal:  J Bacteriol       Date:  1968-11       Impact factor: 3.490

7.  Bactericidal substance produced by Haemophilus influenzae b.

Authors:  R A Venezia; R G Robertson
Journal:  Can J Microbiol       Date:  1975-10       Impact factor: 2.419

8.  Effects of colicins E1 and K on cellular metabolism.

Authors:  K L Fields; S E Luria
Journal:  J Bacteriol       Date:  1969-01       Impact factor: 3.490
  8 in total
  2 in total

1.  Cloning and characterization of the haemocin immunity gene of Haemophilus influenzae.

Authors:  Y M Murley; T D Edlind; J M Pozsgay; J J LiPuma
Journal:  J Bacteriol       Date:  1997-03       Impact factor: 3.490

2.  Interaction of haemocin with Escherichia coli.

Authors:  R G Streker; R A Venezia; R G Robertson
Journal:  Antimicrob Agents Chemother       Date:  1981-04       Impact factor: 5.191
  2 in total

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