Literature DB >> 4007265

Partial rescue of embryos from two maternal-effect neurogenic mutants by transplantation of wild-type ooplasm.

S G LaBonne, A P Mahowald.   

Abstract

We show that embryos produced by Drosophila females homozygous for the maternal-effect neurogenic mutations almondex and pecanex can be partially rescued by microinjection of wild-type ooplasm. In addition, we demonstrate that these mutations fully complement one another with respect to this assay, as they do by classical genetic criteria. Finally, we show that embryos from both mutations cease to be rescuable after the establishment of the syncytial blastoderm. The significance of these results for our understanding of the neurogenic phenotype is discussed.

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Year:  1985        PMID: 4007265     DOI: 10.1016/0012-1606(85)90084-3

Source DB:  PubMed          Journal:  Dev Biol        ISSN: 0012-1606            Impact factor:   3.582


  5 in total

1.  Functional interactions of neurogenic genes of Drosophila melanogaster.

Authors:  A de-la-Concha; U Dietrich; D Weigel; J A Campos-Ortega
Journal:  Genetics       Date:  1988-03       Impact factor: 4.562

2.  Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. I. Loci on the X chromosome.

Authors:  N Perrimon; L Engstrom; A P Mahowald
Journal:  Genetics       Date:  1989-02       Impact factor: 4.562

3.  Reversible commitment of neural and epidermal progenitor cells during embryogenesis of Drosophila melanogaster.

Authors:  Gerhard M Technau; Thomas Becker; Jose A Campos-Ortega
Journal:  Rouxs Arch Dev Biol       Date:  1988-12

4.  Characterization of a region of the X chromosome of Drosophila including multi sex combs (mxc), a Polycomb group gene which also functions as a tumour suppressor.

Authors:  P Santamaría; N B Randsholt
Journal:  Mol Gen Genet       Date:  1995-02-06

5.  EGF homologous sequences encoded in the genome of Drosophila melanogaster, and their relation to neurogenic genes.

Authors:  E Knust; U Dietrich; U Tepass; K A Bremer; D Weigel; H Vässin; J A Campos-Ortega
Journal:  EMBO J       Date:  1987-03       Impact factor: 11.598

  5 in total

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