Literature DB >> 4007241

The subcellular distribution of fumarase isozymes in rat liver.

D F Donnelly, M C O'Hare, S Doonan.   

Abstract

Between 13 and 25% of the fumarase activity of rat liver was found to be cytosolic in origin the remainder being localised in the mitochondria. Electrophoretic analysis on cellulose acetate showed that mitochondria do not contain detectable levels of cytosolic isozyme or vice versa.

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Year:  1985        PMID： 4007241     DOI： 10.1016/0020-711x(85)90128-4

Source DB:  PubMed          Journal:  Int J Biochem        ISSN： 0020-711X


  1 in total

1.  Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors.

Authors:  Ferdia A Gallagher; Mikko I Kettunen; De-En Hu; Pernille R Jensen; René In 't Zandt; Magnus Karlsson; Anna Gisselsson; Sarah K Nelson; Timothy H Witney; Sarah E Bohndiek; Georg Hansson; Torben Peitersen; Mathilde H Lerche; Kevin M Brindle
Journal:  Proc Natl Acad Sci U S A       Date:  2009-11-10       Impact factor: 11.205
  1 in total

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