Literature DB >> 4007055

Glycine antagonism by RU 5135.

D R Curtis, R Malik.   

Abstract

In the spinal cord of the pentobarbitone-anaesthetised cat, microelectrophoretic RU 5135, a steroid derivative, was a potent strychnine-like glycine antagonist, having less effect on the inhibition by GABA of neuronal firing.

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Year:  1985        PMID： 4007055     DOI： 10.1016/0014-2999(85)90569-2

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  3 in total

1.  Clozapine's antipsychotic effects do not depend on blockade of 5-HT3 receptors.

Authors:  R F Squires; E Saederup
Journal:  Neurochem Res       Date:  1999-05       Impact factor: 3.996

2.  A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord.

Authors:  T Saitoh; M Ishida; M Maruyama; H Shinozaki
Journal:  Br J Pharmacol       Date:  1994-09       Impact factor: 8.739

3.  Electrophysiological study of SR 42641, a novel aminopyridazine derivative of GABA: antagonist properties and receptor selectivity of GABAA versus GABAB responses.

Authors:  M Desarmenien; E Desaulles; P Feltz; M Hamann
Journal:  Br J Pharmacol       Date:  1987-02       Impact factor: 8.739
  3 in total

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