| Literature DB >> 4007025 |
R Somers, J Rouësse, A van Oosterom, D Thomas.
Abstract
A phase II study was carried out with 9-hydroxy-methyl-elliptinium (9-HME) in metastatic soft tissue sarcoma. The dose was 100 mg/m2 weekly in 1 1/2 hr intravenous infusion protected from light. Nineteen cases were evaluable for response, all previously treated with other chemotherapy regimens. No remissions were seen. Major toxicities were nausea and vomiting, dryness of the mouth and anorexia. It is concluded that 9-HME is not an effective drug in metastatic soft tissue sarcoma.Entities:
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Year: 1985 PMID： 4007025 DOI： 10.1016/0277-5379(85)90086-0
Source DB: PubMed Journal: Eur J Cancer Clin Oncol ISSN： 0277-5379