Literature DB >> 4006724

The management of preterm labor with the calcium channel-blocking agent nifedipine combined with the beta-mimetic terbutaline.

A F Kaul, R Osathanondh, L E Safon, F D Frigoletto, P A Friedman.   

Abstract

We describe a successful, prolonged, inhibition of preterm labor using nifedipine combined with terbutaline in a patient undergoing complicated obstetrical problems. Delivery was delayed for two months and no significant ill effects were observed in the mother or her infant. This case reports the longest duration and the safe use of nifedipine for tocolysis, to date. A review of reports of the use of calcium channel-blockers in preterm labor is also presented.

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Year:  1985        PMID: 4006724     DOI: 10.1177/106002808501900507

Source DB:  PubMed          Journal:  Drug Intell Clin Pharm        ISSN: 0012-6578


  2 in total

1.  Hyperpolarization and slowing of the rate of contraction in human uterus in pregnancy by prostaglandins E2 and f2alpha: involvement of the Na+ pump.

Authors:  H C Parkington; M A Tonta; N K Davies; S P Brennecke; H A Coleman
Journal:  J Physiol       Date:  1999-01-01       Impact factor: 5.182

2.  Calcium channel blockers as tocolytics: principles of their actions, adverse effects and therapeutic combinations.

Authors:  Róbert Gáspár; Judit Hajagos-Tóth
Journal:  Pharmaceuticals (Basel)       Date:  2013-05-23
  2 in total

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