Literature DB >> 4006536

Summary and recommendations of a workshop on the investigative use of fiberoptic bronchoscopy and bronchoalveolar lavage in asthmatic patients.

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Abstract

The participants in the workshop reached unanimous consensus that as an investigative tool, BAL has enormous potential for extending knowledge of the immunopathogenesis of asthma. When utilized according to these guidelines, maximum knowledge may be gained with minimal risks to study subjects. However, we wish to emphasize that the extent to which the safety of the procedure applies to those asthmatic subjects with more symptoms and an FEV1 of less than 60 percent of predicted remains to be established by carefully controlled clinical investigations.

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Year:  1985        PMID: 4006536     DOI: 10.1378/chest.88.1.136

Source DB:  PubMed          Journal:  Chest        ISSN: 0012-3692            Impact factor:   9.410


  2 in total

1.  Direct evidence of a role for mast cells in the pathogenesis of antigen-induced bronchoconstriction.

Authors:  T B Casale; D Wood; H B Richerson; B Zehr; D Zavala; G W Hunninghake
Journal:  J Clin Invest       Date:  1987-11       Impact factor: 14.808

2.  Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness.

Authors:  T B Casale; D Wood; H B Richerson; S Trapp; W J Metzger; D Zavala; G W Hunninghake
Journal:  J Clin Invest       Date:  1987-04       Impact factor: 14.808

  2 in total

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