| Literature DB >> 4005363 |
C P Klein, K de Groot, A A Driessen, H B van der Lubbe.
Abstract
The biodegradation of different porous beta-whitlockite materials are studied by in vivo experiments, radiographic follow-ups and light microscopy observations. The materials were implanted in rabbit tibiae for 16 month. Micropores play an important role in the biodegradation rate. The resorbing materials evoke an inflammation with plasma cells. The resorption starts in the medulla, and the phagocytosed particles are removed to the lymph nodes. Normal bone function can be restored after all the implant material is resorbed.Entities:
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Year: 1985 PMID： 4005363 DOI： 10.1016/0142-9612(85)90008-0
Source DB: PubMed Journal: Biomaterials ISSN： 0142-9612 Impact factor: 12.479