Literature DB >> 4004849

Guinea pig has a unique mammalian VIP.

B H Du, J Eng, J D Hulmes, M Chang, Y C Pan, R S Yalow.   

Abstract

Mammalian vasoactive intestinal peptide (VIP) has been reported to be identical in four species. This report describes the extraction of guinea pig (GP) intestinal VIP, its purification and sequence. Frozen intestines were extracted in five volumes of methanol and the methanol cakes reextracted with acid. VIP in the acid extract was concentrated onto ion-exchange cellulose and was brought to final purity through a series of HPLC steps. GP VIP differs from other mammalian VIP's by four amino acid substitutions: (sequence in text) This is further evidence that the GP gastroenteropancreatic axis has a unique evolutionary separation from other mammals.

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Year:  1985        PMID： 4004849     DOI： 10.1016/0006-291x(85)91052-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  12 in total

1.  Co-existence and origin of peptidergic and adrenergic nerves in the guinea pig uterus. Retrograde tracing and immunocytochemistry, effects of chemical sympathectomy, capsaicin treatment and pregnancy.

Authors:  P Alm; L M Lundberg
Journal:  Cell Tissue Res       Date:  1988       Impact factor: 5.249

Review 2.  Vasoactive intestinal peptide.

Authors:  S I Said
Journal:  J Endocrinol Invest       Date:  1986-04       Impact factor: 4.256

3.  Receptors for VIP and PACAP in guinea pig cerebral cortex: effects on cyclic AMP synthesis and characterization by 125I-VIP binding.

Authors:  Jolanta B Zawilska; Agnieszka Dejda; Pawel Niewiadomski; Illana Gozes; Jerzy Z Nowak
Journal:  J Mol Neurosci       Date:  2005       Impact factor: 3.444

4.  Immune evasion by Salmonella: exploiting the VPAC1/VIP axis in human monocytes.

Authors:  Basim Askar; John Higgins; Paul Barrow; Neil Foster
Journal:  Immunology       Date:  2019-09-11       Impact factor: 7.397

5.  Receptor binding of guinea pig and pig vasoactive intestinal peptides by rat lung.

Authors:  S Paul; D J Volle; J Currie
Journal:  Biochem J       Date:  1988-09-01       Impact factor: 3.857

Review 6.  Therapeutic potential of vasoactive intestinal peptide and its receptors in neurological disorders.

Authors:  Caitlin M White; Sunggoan Ji; Huan Cai; Stuart Maudsley; Bronwen Martin
Journal:  CNS Neurol Disord Drug Targets       Date:  2010-11       Impact factor: 4.388

Review 7.  Immunomodulation of innate immune responses by vasoactive intestinal peptide (VIP): its therapeutic potential in inflammatory disease.

Authors:  S G R Smalley; P A Barrow; N Foster
Journal:  Clin Exp Immunol       Date:  2009-08       Impact factor: 4.330

8.  An immunohistochemical study of the catecholamine synthesizing enzymes and neuropeptides in the female guinea-pig uterus and vagina.

Authors:  B S Mitchell; E Ahmed
Journal:  Histochem J       Date:  1992-06

9.  Characterization of vasoactive intestinal peptide/pituitary adenylate cyclase-activating polypeptide receptors in chick cerebral cortex.

Authors:  Jolanta B Zawilska; Pawel Niewiadomski; Jerzy Z Nowak
Journal:  J Mol Neurosci       Date:  2003-04       Impact factor: 3.444

10.  Transcriptional modulation by VIP: a rational target against inflammatory disease.

Authors:  Hiba Ibrahim; Paul Barrow; Neil Foster
Journal:  Clin Epigenetics       Date:  2011-05-18       Impact factor: 6.551
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