Literature DB >> 4004725

Certain characteristics of myocardial contractility of isovolumic dog heart at randomly variable heart rhythm.

O N Bershitskaya, L T Lysenko, J L Protsenko, A V Trubetskoy.   

Abstract

The relationship "heart rate - left ventricular pressure" was investigated in the isolated canine heart perfused with constant pressure at different preloads. Rhythmical stimulation was performed with constant stimulus interval duration and with stimulus intervals randomly changed near the average value (150-200 stimuli in series). Correlation and dispersion function analysis show that rhythm dispersion had a negative inotropic effect which was independent of the preload of the ventricle in the range of 120-180 beat/min, but this dependence occurred with low rats of stimulation. This method is proposed for the assessment of contractility under conditions of heart rate variations (physiological and pathological arrhythmias).

Entities:  

Mesh：

Year:  1985        PMID： 4004725     DOI： 10.1007/bf01910463

Source DB:  PubMed          Journal:  Basic Res Cardiol        ISSN： 0300-8428            Impact factor:   17.165


  8 in total

Review 1.  THE INFLUENCE OF THE INTERVAL BETWEEN BEATS ON MYOCARDIAL CONTRACTILITY.

Authors:  J KOCH-WESER; J R BLINKS
Journal:  Pharmacol Rev       Date:  1963-09       Impact factor: 25.468

2.  Effect of rate changes on strength and time course of contraction of papillary muscle.

Authors:  J KOCH-WESER
Journal:  Am J Physiol       Date:  1963-03

3.  Frequency-force relationships of mammalian ventricular muscle in vivo and in vitro.

Authors:  M L Kahn; F Kavaler; V J Fisher
Journal:  Am J Physiol       Date:  1976-03

4.  Inotropic effects of electric currents. I. Positive and negative effects of constant electric currents or current pulses applied during cardiac action potentials. II. Hypotheses: calcium movements, excitation-contraction coupling and inotropic effects.

Authors:  E H Wood; R L Heppner; S Weidmann
Journal:  Circ Res       Date:  1969-03       Impact factor: 17.367

5.  A reexamination of the influence of muscle length on myocardial performance.

Authors:  B R Jewell
Journal:  Circ Res       Date:  1977-03       Impact factor: 17.367

6.  The relation of alternating contractility of the heart to the inotropic effects of rhythm.

Authors:  P Bravený
Journal:  Arch Int Physiol Biochim       Date:  1964-09

7.  [Analysis of depression of contractions of the isolated dog heart following paired stimulation].

Authors:  L T Lysenko; A V Trubetskoĭ
Journal:  Kardiologiia       Date:  1976-11       Impact factor: 0.395

8.  Calcium-movement controlling cardiac contractility II. Analog computation of cardiac excitation-contraction coupling on the basis of calcium kinetics in a multi-compartment model.

Authors:  R Kaufmann; R Bayer; T Fürniss; H Krause; H Tritthart
Journal:  J Mol Cell Cardiol       Date:  1974-12       Impact factor: 5.000
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.