Literature DB >> 4004411

Morphological evaluation of the lipofuscinolytic effect of acetylhomocysteine thiolactone.

E Aloj Totáro, F A Pisanti, A Continillo, E Liberatori.   

Abstract

The acetylhomocysteine thiolactone, a free radical scavenger drug able to activate the superoxide dismutase, shows a lytic effect on neuronal lipofuscin. The study was performed in a nervous tissue particularly rich in lipofuscin, the electric lobe of Torpedo marmorata. It is shown that the drug induces the migration of pigment towards the blood vessels and glial cells which remove them.

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Year:  1985        PMID: 4004411     DOI: 10.1016/0167-4943(85)90019-6

Source DB:  PubMed          Journal:  Arch Gerontol Geriatr        ISSN: 0167-4943            Impact factor:   3.250


  1 in total

1.  Effect of acetylhomocysteine thiolactone on nucleolar cytology and lipofuscinogenesis in electric lobe neurons.

Authors:  H E Enesco; M A Enesco; E Aloj Totaro; F A Pisanti
Journal:  Experientia       Date:  1988-08-15
  1 in total

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