Literature DB >> 4002868

[Tetanus immunity in an urban population: gaps in the vaccination of senior citizens and foreign guest workers].

G T Werner, W E Berdel, N Frühwein.   

Abstract

Immunity against tetanus in an urban population: gaps of immunity among elderly persons. In a sero-epidemiological survey we investigated the immunity against tetanustoxoid in an urban population. Children and adolescents born in Germany (n = 193) showed an excellent immunity, negative findings being the exception. Among soldiers of the army (n = 136), negative findings were rare too. In these both groups the antibody titiers averaged 4,5 IU/ml. It is generally agreed that an antibody titer of 0,01 IU/ml protects against tetanus. Adults born in Germany (n = 295) had a good immunity: 84% showed antibody - titers against tetanus. Among elderly persons, however, above 60 years of age (n = 1576) there was a striking incidence of negative findings: in 1043 persons (65%) no antibodies could be detected. The remaining 533 persons with positive findings (35%) had antibody-titers in the lower range (average 0,482 IU/ml). Also among foreigners and immigrant labourers from mediterrean countries (Greece, Turkey, Yugoslavia) the frequency of negative findings was high: 183 persons were examined, 70 (39%) were negative 113 (61%) were positive. The incidence of negative findings was highest among women from the mediterrean countries. Several small studies published in Switzerland show a similar tendency. Our paper will encourage further seroepidemiological studies.

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Year:  1985        PMID: 4002868     DOI: 10.1007/bf02083054

Source DB:  PubMed          Journal:  Soz Praventivmed        ISSN: 0303-8408


  13 in total

1.  Editorial: The inexcusable disease.

Authors:  G Edsall
Journal:  JAMA       Date:  1976-01-05       Impact factor: 56.272

2.  Immunity to tetanus in Victoria, 1973.

Authors:  J C Trinca
Journal:  Med J Aust       Date:  1974-10-19       Impact factor: 7.738

3.  Tetanus in the United States, 1900-1969. Analysis by cohorts.

Authors:  D W Fraser
Journal:  Am J Epidemiol       Date:  1972-10       Impact factor: 4.897

4.  Tetanus toxoid immunization of adults: a continuing need.

Authors:  G F Brooks; T M Buchanan; J V Bennett
Journal:  Ann Intern Med       Date:  1970-10       Impact factor: 25.391

5.  Age-related decrease in frequencies of B-cell precursors and specific helper T cells involved in the IgG anti-tetanus toxoid antibody production in humans.

Authors:  S Kishimoto; S Tomino; H Mitsuya; H Nishimura
Journal:  Clin Immunol Immunopathol       Date:  1982-10

6.  Antitoxin responses in the elderly to tetanus-diphtheria (TD) immunization.

Authors:  F L Ruben; J Nagel; P Fireman
Journal:  Am J Epidemiol       Date:  1978-08       Impact factor: 4.897

7.  [The epidemiologic situation of infectious disease in West Germany in 1979].

Authors:  H P Pöhn
Journal:  Fortschr Med       Date:  1981-03-05

8.  Tetanus and diphtheria immunity in urban Minnesota adults.

Authors:  K Crossley; P Irvine; J B Warren; B K Lee; K Mead
Journal:  JAMA       Date:  1979-11-23       Impact factor: 56.272

9.  Immunity to tetanus in Finland.

Authors:  M K Viljanen; S Nieminen
Journal:  Scand J Infect Dis       Date:  1980

10.  [Tetanus immunity during senescence (author's transl)].

Authors:  H Finger; E Habermann; K Bracharz; H Hof
Journal:  Zentralbl Bakteriol Orig B       Date:  1975-10
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  1 in total

1.  Tetanus in Switzerland 1980-1989.

Authors:  P L Zuber; A Schierz; G Aréstegui; R Steffen
Journal:  Eur J Epidemiol       Date:  1993-11       Impact factor: 8.082

  1 in total

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