Literature DB >> 4000175

Orthophenylphenol mutagenicity in a human cell strain.

H Suzuki, N Suzuki, M Sasaki, K Hiraga.   

Abstract

Orthophenylphenol (OPP), a widely used fungicide, induced ouabain-resistant (OuaR) mutants in a ultraviolet (UV)-sensitive human RSa cell strain and the frequencies increased in a dose-related fashion. OPP was a more potent mutagen than UV at doses related to equal survival. These results suggest that OPP has a mutagenic activity and that further experiments on this chemical are warranted.

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Year:  1985        PMID： 4000175     DOI： 10.1016/0165-1218(85)90015-1

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  4 in total

1.  Effect of buthionine sulfoximine on orthophenylphenol-induced hepato- and nephrotoxic potential in male rats.

Authors:  Y Nakagawa; K Tayama
Journal:  Arch Toxicol       Date:  1988       Impact factor: 5.153

2.  Novel metabolic markers for the risk of diabetes development in American Indians.

Authors:  Jinying Zhao; Yun Zhu; Noorie Hyun; Donglin Zeng; Karan Uppal; ViLinh T Tran; Tianwei Yu; Dean Jones; Jiang He; Elisa T Lee; Barbara V Howard
Journal:  Diabetes Care       Date:  2014-12-02       Impact factor: 19.112

3.  Urothelial damage and tumor initiation by urinary metabolites of sodium o-phenylphenate in the urinary bladder of female rats.

Authors:  R Hasegawa; F Furukawa; K Toyoda; H Sato; M Takahashi; Y Hayashi
Journal:  Jpn J Cancer Res       Date:  1990-05

4.  Sex differences in o-phenylphenol and sodium o-phenylphenate rat urinary bladder carcinogenesis: urinary metabolites and electrolytes under conditions of aciduria and alkalinuria.

Authors:  R Hasegawa; M Fukuoka; T Takahashi; A Yamamoto; S Yamaguchi; M A Shibata; A Tanaka; S Fukushima
Journal:  Jpn J Cancer Res       Date:  1991-06
  4 in total

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