Literature DB >> 4000042

Plasma warfarin concentrations after a massive overdose.

L P Hackett, K F Ilett, A Chester.   

Abstract

The plasma pharmacokinetics of warfarin were studied in a patient who took an overdose of warfarin (2000 mg by mouth), together with 25 X 10(4) units of heparin administered subcutaneously. The plasma warfarin level fell rapidly (half-life, 21.7 h), and there was no convincing evidence for dose-dependency in its disposition.

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Year:  1985        PMID: 4000042     DOI: 10.5694/j.1326-5377.1985.tb113560.x

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  3 in total

1.  Warfarin overdose: a 25-year experience.

Authors:  Michael Levine; Anthony F Pizon; Angela Padilla-Jones; Anne-Michelle Ruha
Journal:  J Med Toxicol       Date:  2014-06

2.  Warfarin Overdose in an Adolescent Not Dependent on Anticoagulation: Reversal Strategy and Kinetics.

Authors:  C James Watson; Michael D Simpson; James D Whitledge; Al Patterson; Michele M Burns
Journal:  J Med Toxicol       Date:  2022-09-06

3.  Attempted Suicide by Massive Warfarin Ingestion Conservatively Managed Using Phytonadione.

Authors:  Katherine L March; Kruti S Patel; Jennifer D Twilla
Journal:  Case Rep Hematol       Date:  2016-12-04
  3 in total

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