Spectrum of renal abnormalities in acquired immune-deficiency syndrome.

Data from 27 patients with acquired immunedeficiency syndrome (AIDS) and AIDS-related complex (ARC) managed at the University of California, Irvine Medical Center since 1982 were extracted from medical records. Functional renal insufficiency occurred with considerable frequency among the AIDS patients. In contrast renal function was stable in the ARC patients studied. The majority of the AIDS patients exhibited persistent or transient proteinuria. Hematuria, leukocyturia, bacteruria, and nonvenereal urinary tract infections were seen with considerable frequency among AIDS patients and much less frequently among ARC patients. Similarly various disorders of fluids, electrolytes, acid base and abnormal phosphorus and calcium levels were common among AIDS patients and uncommon among ARC patients. These observations point to the prevalence and significance of the renal and associated abnormalities in acquired immune-deficiency syndrome.