Literature DB >> 3999115

Characterization of Gilbert-like syndrome in squirrel monkeys (Saimiri sciureus).

C E Cornelius, P A Rodgers, M L Bruss, C E Ahlfors.   

Abstract

Bolivian squirrel monkeys, unlike those of Brazilian origin, exhibit a marked fasting hyperbilirubinemia (FH) similar to that observed in Gilbert's syndrome in man. Since no delays in the hepatic clearance of sulfobromophthalein or indocyanine green are present, the Bolivian monkey appears to be similar to Gilbert's type I syndrome. FH can be significantly decreased by either phenobarbital or tin-protoporphyrin pretreatment. Nicotinic acid-induced hyperbilirubinemia and delayed tolbutamide clearance were not observed as in the human syndrome.

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Year:  1985        PMID： 3999115

Source DB:  PubMed          Journal:  J Med Primatol        ISSN： 0047-2565            Impact factor:   0.667


  3 in total

1.  Sn-protoporphyrin inhibition of fetal and neonatal brain heme oxygenase. Transplacental passage of the metalloporphyrin and prenatal suppression of hyperbilirubinemia in the newborn animal.

Authors:  G S Drummond; A Kappas
Journal:  J Clin Invest       Date:  1986-03       Impact factor: 14.808

2.  Studies with the haeme oxygenase inhibitor Sn-protoporphyrin in patients with primary biliary cirrhosis and idiopathic haemochromatosis.

Authors:  L Berglund; B Angelin; R Hultcrantz; K Einarsson; L Emtestam; G Drummond; A Kappas
Journal:  Gut       Date:  1990-08       Impact factor: 23.059

3.  Bilirubin excretion and bile flow in fed and fasted Brazilian squirrel monkeys (Saimiri sciureus).

Authors:  C E Cornelius; B A Myers; M L Bruss; J W George
Journal:  Vet Res Commun       Date:  1989       Impact factor: 2.459
  3 in total

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