Literature DB >> 3996604

Changes in the glutathione status of plasma, liver and muscle following exhaustive exercise in rats.

H Lew, S Pyke, A Quintanilha.   

Abstract

Our results show that following physical exercise to exhaustion, the levels of reduced glutathione are increased in the plasma, but decreased in both the liver and skeletal muscle of rats. Levels of glutathione disulfide are increased in all 3 tissues. Our results are consistent with a mechanism in which the liver may be dumping reduced glutathione into the plasma in an attempt to deliver it to those tissues that need it the most: in this case, skeletal muscle.

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Year:  1985        PMID: 3996604     DOI: 10.1016/0014-5793(85)80919-4

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  33 in total

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2.  Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat.

Authors:  S C Lu; J Kuhlenkamp; C Garcia-Ruiz; N Kaplowitz
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3.  Alterations in tissue glutathione antioxidant system in streptozotocin-induced diabetic rats.

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4.  Tissue protection against oxidative stress.

Authors:  S Di Meo; P Venditti; T De Leo
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5.  Effect of exercise on tissue anti-oxidant capacity and heart electrical properties in male and female rats.

Authors:  P Venditti; M C Piro; G Artiaco; S Di Meo
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1996

6.  Hepatic mitochondrial adaptations to physical activity: impact of sexual dimorphism, PGC1α and BNIP3-mediated mitophagy.

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7.  Role of iron in oxidative stress in skeletal muscle atrophied by immobilization.

Authors:  H Kondo; M Miura; J Kodama; S M Ahmed; Y Itokawa
Journal:  Pflugers Arch       Date:  1992-06       Impact factor: 3.657

8.  Effects of endurance training and exercise on tissue antioxidative capacity and acetaminophen detoxification.

Authors:  H Lew; A Quintanilha
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1991 Jan-Mar       Impact factor: 2.441

9.  Effect of thermal stress on glutathione metabolism in human erythrocytes.

Authors:  Y Ohtsuka; N Yabunaka; H Fujisawa; I Watanabe; Y Agishi
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1994

10.  Do invading leucocytes contribute to the decrease in glutathione concentrations indicating oxidative stress in exercised muscle, or are they important for its recovery?

Authors:  J A Duarte; F Carvalho; M L Bastos; J M Soares; H J Appell
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1994
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