Literature DB >> 3996535

Naloxone prevents the analgesic action of alpha-MSH in mice.

T Ohkubo, M Shibata, H Takahashi, S Naruse.   

Abstract

alpha-MSH (0.1, 1, 10 micrograms) was administered intracerebroventricularly and its action on pain sensitivity was investigated by the hot-plate method in mice. alpha-MSH produced dose-dependent analgesia and this analgesic effect was prevented by naloxone (1 mg/kg, s.c.). It is possible that alpha-MSH may play a role in the mechanism of pain through endogeneous opioid systems.

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Year:  1985        PMID： 3996535     DOI： 10.1007/bf02007691

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

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Authors:  T J HALEY; W G MCCORMICK
Journal:  Br J Pharmacol Chemother       Date:  1957-03

2.  The induction of excessive grooming in the rat by intraventricular application of peptides derived from ACTH: structure-activity studies.

Authors:  W H Gispen; V M Wiegant; H M Greven; D de Wied
Journal:  Life Sci       Date:  1975-08-15       Impact factor: 5.037

3.  Influence of peptides on reduced response of rats to electric footshock after acute administration of morphine.

Authors:  W H Gispen; T B Van Wimersma Greidanus; C Waters-Ezrin; E Zimmermann; W A Krivoy; D De Wied
Journal:  Eur J Pharmacol       Date:  1975-08       Impact factor: 4.432

4.  ACTH-like peptides and morphine: interaction at the level of the CNS.

Authors:  V M Wiegant; W H Gispen; L Terenius; D de Wied
Journal:  Psychoneuroendocrinology       Date:  1977       Impact factor: 4.905

5.  Melanocyte-stimulating hormone and learned appetitive behavior.

Authors:  C A Sandman; A J Kastin; A V Schally
Journal:  Experientia       Date:  1969-09-15

6.  Immunocytochemical localization of alpha-melanocyte stimulating hormone (alpha-MSH)-like compounds in the rat nervous system.

Authors:  D F Swaab; B Fisser
Journal:  Neurosci Lett       Date:  1978-03       Impact factor: 3.046

7.  Distribution of 3H-alpha-MSH in rat brain.

Authors:  A J Kastin; C Nissen; K Nikolics; K Medzihradszky; D H Coy; I Teplan; A V Schally
Journal:  Brain Res Bull       Date:  1976 Jan-Feb       Impact factor: 4.077

8.  Induction of analgesia by central administration of ORG 2766, an analog of ACTH4--9.

Authors:  J M Walker; G G Berntson; C A Sandman; A J Kastin; H Akil
Journal:  Eur J Pharmacol       Date:  1981-01-05       Impact factor: 4.432

9.  Common precursor to corticotropins and endorphins.

Authors:  R E Mains; B A Eipper; N Ling
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205

10.  Effects of morphine and beta-endorphin on basal and elevated plasma levels of alpha-MSH and vasopressin.

Authors:  T B van Wimersma Greidanus; T J Thody; H Verspaget; G A de Rotte; H J Goedemans; G Croiset; J M van Ree
Journal:  Life Sci       Date:  1979-02-12       Impact factor: 5.037
  10 in total
  4 in total

1.  The effect of semax on animal pain sensitivity in various experimental models.

Authors:  D M Ivanova; N G Levitskaya; L A Andreeva; L Yu Alfeeva; A A Kamenskii; N F Myasoedov
Journal:  Dokl Biol Sci       Date:  2003 Jan-Feb

Review 2.  Synaptic changes induced by melanocortin signalling.

Authors:  Vanni Caruso; Malin C Lagerström; Pawel K Olszewski; Robert Fredriksson; Helgi B Schiöth
Journal:  Nat Rev Neurosci       Date:  2014-02       Impact factor: 34.870

3.  The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans.

Authors:  Jeffrey S Mogil; Sonya G Wilson; Elissa J Chesler; Andrew L Rankin; Kumar V S Nemmani; William R Lariviere; M Kristina Groce; Margaret R Wallace; Lee Kaplan; Roland Staud; Timothy J Ness; Toni L Glover; Magda Stankova; Alexander Mayorov; Victor J Hruby; Judith E Grisel; Roger B Fillingim
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-27       Impact factor: 11.205

4.  Peripheral analgesic activities of peptides related to alpha-melanocyte stimulating hormone and interleukin-1 beta 193-195.

Authors:  S Poole; A F Bristow; B B Lorenzetti; R E Das; T W Smith; S H Ferreira
Journal:  Br J Pharmacol       Date:  1992-06       Impact factor: 8.739
  4 in total

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