| Literature DB >> 3995551 |
K Inoue, S Tanaka, K Kurosumi.
Abstract
The proliferation of gonadotropes in the anterior pituitary of the castrated male rat was examined immunohistochemically after colchicine treatment. The results show a more than 10-fold increase in mitotic frequency in gonadotropes 1 or 2 weeks after castration, as compared with controls. This result explains the increase in the population of immunoreactive LH cells in castrated male rats. The gonadotropes decreased significantly 1 month after castration. The mitotic activity of gonadotropes was almost completely suppressed in castrates implanted with a silastic tube filled with testosterone.Entities:
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Year: 1985 PMID: 3995551 DOI: 10.1007/bf00222334
Source DB: PubMed Journal: Cell Tissue Res ISSN: 0302-766X Impact factor: 5.249