Literature DB >> 399527

Effect of prostacyclin on antigen induced immediate bronchoconstriction in asthmatic patients.

S Bianco, M Robuschi, A Grugni, R Ceserani, C Gandolfi.   

Abstract

The effect of premedication with inhaled prostacyclin (PGI2) on the allergen induced immediate bronchoconstriction was investigated in 10 asthmatic patients, under single blind conditions, by means of a body plethysmograph. Statistical analysis (Dunnett's test) did not show any significant difference between PGI2 and placebo. The possible meaning of these results is discussed.

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Year:  1979        PMID： 399527     DOI： 10.1016/0161-4630(79)90014-4

Source DB:  PubMed          Journal:  Prostaglandins Med        ISSN： 0161-4630


  7 in total

Review 1.  Prostaglandins and the lung.

Authors:  S P Hanley
Journal:  Lung       Date:  1986       Impact factor: 2.584

2.  Sequential histamine inhalations cause increased bronchial histamine reactivity in guinea pigs: role of platelets, thromboxanes and prostacyclin.

Authors:  W Dorsch; C Hintschich; J Neuhauser; J Weber
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-09       Impact factor: 3.000

3.  Prostanoid receptors involved in the relaxation of human bronchial preparations.

Authors:  X Norel; L Walch; C Labat; J P Gascard; E Dulmet; C Brink
Journal:  Br J Pharmacol       Date:  1999-02       Impact factor: 8.739

Review 4.  The role of prostaglandins in allergic lung inflammation and asthma.

Authors:  Dru Claar; Tina V Hartert; Ray Stokes Peebles
Journal:  Expert Rev Respir Med       Date:  2014-12-26       Impact factor: 3.772

5.  In vivo allergen tachyphylaxis in guinea pig lung is mediated by endogenous prostaglandin E biosynthesis.

Authors:  W Dorsch; L Frey; W Müller
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-03       Impact factor: 3.000

Review 6.  Prostaglandins in asthma and allergic diseases.

Authors:  R Stokes Peebles
Journal:  Pharmacol Ther       Date:  2018-08-03       Impact factor: 12.310

Review 7.  The Biology of Prostaglandins and Their Role as a Target for Allergic Airway Disease Therapy.

Authors:  Kijeong Lee; Sang Hag Lee; Tae Hoon Kim
Journal:  Int J Mol Sci       Date:  2020-03-08       Impact factor: 5.923
  7 in total

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