Recurrence of periphlebitis retinae in multiple sclerosis.

Periphlebitis retinae (PR) in multiple sclerosis (MS) is defined as ophthalmoscopically visible cuffs around veins in the otherwise normal retina. PR in MS has been suggested to be of a recurring nature, but to the authors knowledge this is the first study in which PR in MS has been seen to recur. A recurrence of PR in MS reflects the neurological progress. The material is unique because of the span of years these patients have been followed. In the 4 patients here presented the interval between the two episodes of PR was 16, 13, 5 and 0.5 years, respectively.