Literature DB >> 3992878

Effect of parasitism with Ostertagia circumcincta on pharmacokinetics of fenbendazole in sheep.

S E Marriner, E S Evans, J A Bogan.   

Abstract

Plasma and abomasal fluid concentrations of fenbendazole and its two major metabolites in sheep experimentally infected with Ostertagia circumcincta were compared with those in the same sheep when non-parasitised. Bio-availability of the drug was reduced in the parasitised state. There was also a reduction in the proportion of drug present in the form of metabolites in parasitised as compared with non-parasitised animals.

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Year:  1985        PMID: 3992878     DOI: 10.1016/0304-4017(85)90036-6

Source DB:  PubMed          Journal:  Vet Parasitol        ISSN: 0304-4017            Impact factor:   2.738


  4 in total

1.  The influence of parasitism on the pharmacokinetics of moxidectin in lambs.

Authors:  Anne Lespine; Jean-François Sutra; Jacques Dupuy; Michel Alvinerie; Gilles Aumont
Journal:  Parasitol Res       Date:  2004-05-01       Impact factor: 2.289

2.  Influence of subclinical nematodosis on the kinetic disposition of fenbendazole in buffaloes.

Authors:  A C Mathur; P K Sanyal; S Sarkar
Journal:  Vet Res Commun       Date:  1995       Impact factor: 2.459

3.  Exploring flubendazole formulations for use in sheep. Pharmacokinetic evaluation of a cyclodextrin-based solution.

Authors:  Laura Ceballos; Laura Moreno; Juan J Torrado; Carlos Lanusse; Luis Alvarez
Journal:  BMC Vet Res       Date:  2012-05-28       Impact factor: 2.741

4.  Assessment of Diet-Related Changes on Albendazole Absorption, Systemic Exposure, and Pattern of Urinary Excretion in Treated Human Volunteers.

Authors:  L Ceballos; E Nieves; M Juárez; R Aveldaño; M Travacio; J Martos; R Cimino; J L Walson; A Krolewiecki; C Lanusse; L Alvarez
Journal:  Antimicrob Agents Chemother       Date:  2021-08-17       Impact factor: 5.191

  4 in total

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