Literature DB >> 3992017

Possible interrelations of acetyl-homocysteine-thiolactone in mechanisms of lipofuscinogenesis.

E Aloj Totaro, F A Pisanti, E Liberatori.   

Abstract

The administration of acetyl-homocysteine-thiolactone (cythiolone) to Torpedo marmorata inhibits the production of neuronal lipofuscin. The possible mechanism of this action has been investigated. A free radical scavenger effect of the drug has been demonstrated both in vivo and in vitro. Cythiolone is able to activate the enzyme superoxide dismutase, while no effect has been detected on catalase activity.

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Year:  1985        PMID: 3992017

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN: 0034-5164


  3 in total

1.  Effect of acetylhomocysteine thiolactone on nucleolar cytology and lipofuscinogenesis in electric lobe neurons.

Authors:  H E Enesco; M A Enesco; E Aloj Totaro; F A Pisanti
Journal:  Experientia       Date:  1988-08-15

2.  Protection by free oxygen radical scavenging enzymes against glucose-induced embryonic malformations in vitro.

Authors:  U J Eriksson; L A Borg
Journal:  Diabetologia       Date:  1991-05       Impact factor: 10.122

3.  Oxygen free radical scavengers protect rat islet cells from damage by cytokines.

Authors:  W Sumoski; H Baquerizo; A Rabinovitch
Journal:  Diabetologia       Date:  1989-11       Impact factor: 10.122

  3 in total

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