| Literature DB >> 3992011 |
E C de Ferreyra, O M de Fenos, J A Castro.
Abstract
Four anticalmodulin drugs: trifluoperazine (TFP), pimozide (PMZ), thioridazine (TDZ) and imipramine (IMP) (50 mg/kg, ip) were able to partially prevent Galactosamine (GAL) (600 mg/kg, ip) induced liver necrosis when given 6 h after the hepatotoxin. IMP was also effective 10 h after GAL. The possibility of calmodulin participation in late stages of GAL-induced liver injury is analyzed.Entities:
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Year: 1985 PMID： 3992011
Source DB: PubMed Journal: Res Commun Chem Pathol Pharmacol ISSN： 0034-5164