Literature DB >> 3991409

Hyperlipidaemia and premature coronary artery disease associated with sex-change in a female.

C K ffrench-Constant, F A Spengel, G R Thompson.   

Abstract

We describe the management of a genotypic female who developed hyperlipidaemia and premature coronary artery disease following bilateral oophorectomy and methyltestosterone administration, and present evidence to suggest that the therapeutic androgenization involved in the sex-change was responsible for the hyperlipidaemia.

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Year:  1985        PMID: 3991409      PMCID: PMC2418125          DOI: 10.1136/pgmj.61.711.61

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  14 in total

1.  Increased incidence of coronary heart disease in women castrated prior to the menopause.

Authors:  R W ROBINSON; N HIGANO; W D COHEN
Journal:  Arch Intern Med       Date:  1959-12

2.  The influence of gonadal hormones on serum lipids and lipoproteins: studies in normal and hypogonadal subjects.

Authors:  R H FURMAN; R P HOWARD
Journal:  Ann Intern Med       Date:  1957-11       Impact factor: 25.391

3.  The effects of estrogens on serum lipids in women.

Authors:  R W ROBINSON; N HIGANO; W D COHEN
Journal:  AMA Arch Intern Med       Date:  1957-11

4.  Endocrine aspects of coronary sclerosis.

Authors:  G S BOYD; M F OLIVER
Journal:  Lancet       Date:  1956-12-22       Impact factor: 79.321

5.  Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.

Authors:  W T Friedewald; R I Levy; D S Fredrickson
Journal:  Clin Chem       Date:  1972-06       Impact factor: 8.327

6.  Changes in cholesterol pool size, turnover rate, and fecal bile acid and sterol excretion after partial ileal bypass in hypercholesteremic patients.

Authors:  R B Moore; I D Frantz; H Buchwald
Journal:  Surgery       Date:  1969-01       Impact factor: 3.982

7.  Estrogen use and all-cause mortality. Preliminary results from the Lipid Research Clinics Program Follow-Up Study.

Authors:  T L Bush; L D Cowan; E Barrett-Connor; M H Criqui; J M Karon; R B Wallace; H A Tyroler; B M Rifkind
Journal:  JAMA       Date:  1983-02-18       Impact factor: 56.272

8.  Effects of different progestogens on lipoproteins during postmenopausal replacement therapy.

Authors:  E Hirvonen; M Mälkönen; V Manninen
Journal:  N Engl J Med       Date:  1981-03-05       Impact factor: 91.245

9.  Receptor-mediated low density lipoprotein catabolism in man.

Authors:  J Shepherd; S Bicker; A R Lorimer; C J Packard
Journal:  J Lipid Res       Date:  1979-11       Impact factor: 5.922

10.  Regulation of hepatic lipoprotein receptors in the dog. Rapid regulation of apolipoprotein B,E receptors, but not of apolipoprotein E receptors, by intestinal lipoproteins and bile acids.

Authors:  B Angelin; C A Raviola; T L Innerarity; R W Mahley
Journal:  J Clin Invest       Date:  1983-04       Impact factor: 14.808

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