Literature DB >> 3987871

NADP-isocitric dehydrogenase of gerbil adrenal mitochondria: support of steroid hydroxylation.

J L McCarthy, J Gauthier.   

Abstract

In gerbil adrenal cortex the activity of intramitochondrial NADP-linked isocitric dehydrogenase (IDH) is up to 10-fold greater than the NAD-linked IDH. The NADP-IDH, apparent Km 0.58 mM, Vmax 280 nmoles/min/mg mitochondrial protein, appears to be the major source of reducing equivalents to support adrenal mitochondrial steroid 11B- and 19-hydroxylation in this species.

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Year:  1985        PMID: 3987871     DOI: 10.1007/bf01966160

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  5 in total

1.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

Review 2.  Metabolic events associated with steroid hydroxylation by the adrenal cortex.

Authors:  E R Simpson; D Y Cooper; R W Estabrook
Journal:  Recent Prog Horm Res       Date:  1969

Review 3.  Regulation by ACTH of steroid hormone biosynthesis in the adrenal cortex.

Authors:  E R Simpson; M R Waterman
Journal:  Can J Biochem Cell Biol       Date:  1983-07

4.  Induction of 17 alpha-hydroxylase (cytochrome P-450(17)alpha) activity by adrenocorticotropin in bovine adrenocortical cells maintained in monolayer culture.

Authors:  J L McCarthy; R E Kramer; B Funkenstein; E R Simpson; M R Waterman
Journal:  Arch Biochem Biophys       Date:  1983-04-15       Impact factor: 4.013

5.  The 19-hydroxylase of the gerbil adrenal gland: a mitochondrial enzyme.

Authors:  J L McCarthy; A Dickinson
Journal:  Proc Soc Exp Biol Med       Date:  1980-10
  5 in total

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