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Literature DB >> 3987733

Fatty acid composition of plasma lipids in acrodermatitis enteropathica before and after zinc supplementation.

B Koletzko, A Bretschneider, H J Bremer.

Abstract

The fatty acid composition of different plasma lipid fractions has been estimated in a 6-month-old girl with acrodermatitis enteropathica before and after zinc supplementation. Linoleic acid and its metabolites were extremely reduced in triglycerides and sterol-esters. In contrast, n-3-fatty acids were increased in sterol-esters and phospholipids. Zinc supplementation led to quick clinical improvement, and linoleic and arachidonic acid increased rapidly in triglycerides and sterol-esters to the values of healthy infants. Fatty acids of phospholipids remained relatively stable. Our findings could be explained by impaired enteral absorption of linoleic acid. Further attention should be directed to the supply and metabolism of essential fatty acids in acrodermatitis enteropathica.

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Year: 1985 PMID： 3987733 DOI： 10.1007/bf00442310

Source DB: PubMed Journal: Eur J Pediatr ISSN： 0340-6199 Impact factor: 3.183

33 in total

1. Gas chromatographic analysis of the fatty acid composition of the plasma lipids in normal and diabetic subjects.

Authors: B HALLGREN; S STENHAGEN; A SVANBORG; L SVENNERHOLM
Journal: J Clin Invest Date: 1960-09 Impact factor: 14.808

2. Acrodermatitis enteropathica. A clinical and biochemical survey.

Authors: K H Neldner; L Hagler; W R Wise; F B Stifel; E G Lufkin; R H Herman
Journal: Arch Dermatol Date: 1974-11

3. Treatment of acrodermatitis enteropathica by intravenous amino acid hydrolysate.

Authors: S Freier; J Faber; R Goldstein; M Mayer
Journal: J Pediatr Date: 1973-01 Impact factor: 4.406

4. Serum fatty acids before and after recovery from acrodermatitis enteropathica: comparison of an infant with her family.

Authors: H B White; J M Montalvo
Journal: J Pediatr Date: 1973-12 Impact factor: 4.406

5. Acrodermatitis enteropathica with immune deficiency.

Authors: R Julius; M Schulkind; T Sprinkle; O Rennert
Journal: J Pediatr Date: 1973-12 Impact factor: 4.406

6. Role of zinc in linoleic acid desaturation and prostaglandin synthesis.

Authors: S C Cunnane; Y S Huang; D F Horrobin; J Davignon
Journal: Prog Lipid Res Date: 1981 Impact factor: 16.195

7. Effect of sex and age on fatty acid composition of human serum lipids.

Authors: R T Holman; L Smythe; S Johnson
Journal: Am J Clin Nutr Date: 1979-12 Impact factor: 7.045

8. Interactions between zinc, essential fatty acids and prostaglandins: relevance to acrodermatitis enteropathica, total parenteral nutrition, the glucagonoma syndrome, diabetes, anorexia nervosa and sickle cell anaemia.

Authors: D F Horrobin; S C Cunnane
Journal: Med Hypotheses Date: 1980-03 Impact factor: 1.538

9. Maternal essential fatty acid supplementation increases zinc absorption in neonatal rats: relevance to the defect in zinc absorption in acrodermatitis enteropathica.

Authors: S C Cunnane
Journal: Pediatr Res Date: 1982-08 Impact factor: 3.756

Review 10. Polyunsaturated fatty acids in the low-birth-weight infant.

Authors: Z Friedman
Journal: Semin Perinatol Date: 1979-10 Impact factor: 3.300

6 in total

1. Fatty acid composition of plasma lipids in Nigerian children with protein-energy malnutrition.

Authors: B Koletzko; P O Abiodun; M D Laryea; H J Bremer
Journal: Eur J Pediatr Date: 1986-04 Impact factor: 3.183

2. Acrodermatitis enteropathica with normal serum zinc levels: diagnostic value of small bowel biopsy and essential fatty acid determination.

Authors: D Mack; B Koletzko; S Cunnane; E Cutz; A Griffiths
Journal: Gut Date: 1989-10 Impact factor: 23.059