| Literature DB >> 3986536 |
Abstract
The influence of cytoplasmic acidification on dye-coupling between CA3 pyramidal neurons was examined by Lucifer yellow injections in guinea pig hippocampal brain slices. Neurons were believed to be acidified by exposure to 100 mM propionate. Dye-coupling was reduced significantly to 6% (n = 35) in propionate versus 28% (n = 39) in control solution (P less than 2%). Propionate may be a useful tool for experimental manipulation of coupling in the mammalian CNS.Entities:
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Year: 1985 PMID： 3986536 DOI： 10.1016/0006-8993(85)90015-0
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252