Literature DB >> 3986129

Effect of (+)-cyanidanol-3 on rat brain lipid peroxidation.

J Fehér, A Blázovics, A Cornides, A Vereckei.   

Abstract

Non-enzymic lipid peroxidation was stimulated in homogenates, plasma membrane fractions and microsomes of rat brain in vitro by incubation with ascorbic acid. Malondialdehyde formation was determined by the thiobarbituric acid test. It has been established that (+)-cyanidanol-3 inhibits the ascorbic acid-stimulated lipid peroxidation in various fractions of rat brain. On the basis of these results it is suggested that (+)-cyanidanol-3 treatment protects brain suspensions against lipid peroxidation by acting as a free radical scavenger in vitro.

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Year:  1985        PMID： 3986129      PMCID： PMC2041046     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  6 in total

1.  Lipid peroxidation as the cause of the ascorbic acid induced decrease of adenosine triphosphatase activities of rat brain microsomes and its inhibition by biogenic amines and psychotropic drugs.

Authors:  A Schaefer; M Komlós; A Seregi
Journal:  Biochem Pharmacol       Date:  1975-10-01       Impact factor: 5.858

2.  Reduced triphosphopyridine nucleotide oxidase-catalyzed alterations of membrane phospholipids. VI. Structural changes in mitochondria associated with inactivation of electron transport activity.

Authors:  P M Pfeifer; P B McCay
Journal:  J Biol Chem       Date:  1972-11-10       Impact factor: 5.157

3.  Antioxidants, lipid peroxidation and chemical-induced liver injury.

Authors:  N R Di Luzio
Journal:  Fed Proc       Date:  1973-08

4.  Protective effect of (+)cyanidanol-3 in acute liver injury induced by galactosamine or carbon tetrachloride in the rat.

Authors:  D Perrissoud; I Weibel
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980-07       Impact factor: 3.000

5.  Biochemical markers in carbon-tetrachloride-and galactosamine-induced acute liver injuries: the effects of dihydroquinoline-type antioxidants.

Authors:  J Fehér; Z Bar-Pollák; L Sréter; E Fehér; H Toncsev
Journal:  Br J Exp Pathol       Date:  1982-08

6.  Enzymic lipid peroxidation in the microsomal fraction of rat brain.

Authors:  T J Player; A A Horton
Journal:  J Neurochem       Date:  1981-08       Impact factor: 5.372
  6 in total

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