Literature DB >> 398481

The use of cefaclor in the treatment of beta-haemolytic streptococcal throat infections in children.

F A Disney, B B Breese, A B Francis, J L Green, W B Talpey.   

Abstract

Cefaclor was used as a therapeutic agent in beta-haemolytic streptococcal throat infections in children in 3 separate studies. Although the numbers of patients in these ongoing studies are too small for valid statistical analysis, cefaclor was found to be (1) an effective agent in a dose of 20 mg/kg/day, (2) as effective as phenoxymethyl penicillin at identical dosages, and (3) equally effective at doses administered twice daily or thrice daily. It was well accepted by the patients, had minimal side effects, and produced no adverse effects in the peripheral blood.

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Year:  1979        PMID: 398481

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  8 in total

Review 1.  Rational prescribing of antibacterials in ambulatory children.

Authors:  J E Hoppe
Journal:  Pharmacoeconomics       Date:  1996-12       Impact factor: 4.981

2.  Randomized, single-blind evaluation of cefadroxil and phenoxymethyl penicillin in the treatment of streptococcal pharyngitis.

Authors:  M E Pichichero; F A Disney; G H Aronovitz; W B Talpey; J L Green; A B Francis
Journal:  Antimicrob Agents Chemother       Date:  1987-06       Impact factor: 5.191

Review 3.  Treatment of respiratory tract infections with cephalosporin antibiotics.

Authors:  R Finch
Journal:  Drugs       Date:  1987       Impact factor: 9.546

Review 4.  Comparison of European and U.S. results for cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis.

Authors:  M Pichichero; J Casey
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2006-06       Impact factor: 3.267

5.  Cefprozil versus penicillin V in treatment of streptococcal tonsillopharyngitis.

Authors:  D Milatovic; D Adam; H Hamilton; E Materman
Journal:  Antimicrob Agents Chemother       Date:  1993-08       Impact factor: 5.191

Review 6.  Different antibiotic treatments for group A streptococcal pharyngitis.

Authors:  Mieke L van Driel; An Im De Sutter; Hilde Habraken; Sarah Thorning; Thierry Christiaens
Journal:  Cochrane Database Syst Rev       Date:  2016-09-11

7.  Pharmacodynamic analysis and clinical trial of amoxicillin sprinkle administered once daily for 7 days compared to penicillin V potassium administered four times daily for 10 days in the treatment of tonsillopharyngitis due to Streptococcus pyogenes in children.

Authors:  M E Pichichero; J R Casey; S L Block; R Guttendorf; H Flanner; D Markowitz; S Clausen
Journal:  Antimicrob Agents Chemother       Date:  2008-03-10       Impact factor: 5.191

8.  Different antibiotic treatments for group A streptococcal pharyngitis.

Authors:  Mieke L van Driel; An Im De Sutter; Sarah Thorning; Thierry Christiaens
Journal:  Cochrane Database Syst Rev       Date:  2021-03-17
  8 in total

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