Literature DB >> 3983963

Toxicity determined in vitro by morphological alterations and neutral red absorption.

E Borenfreund, J A Puerner.   

Abstract

A method is described which combines the use of a visual morphological cytotoxicity assay with a quantitative neutral red (NR) spectrophotometric test, for the assessment of the effect of toxic agents on 3T3 cells in culture. These sensitive and reproducible assays lend themselves to a screening procedure of potential toxicants which can help reduce the use of animals for toxicity testing.

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Year:  1985        PMID： 3983963     DOI： 10.1016/0378-4274(85)90046-3

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN： 0378-4274            Impact factor:   4.372


  233 in total

1.  A possibility for new evaluating method of cytotoxicity by using heat shock protein assay.

Authors:  H Oshima; T Hatayama; M Nakamura
Journal:  J Mater Sci Mater Med       Date:  1997-03       Impact factor: 3.896

2.  The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM).

Authors:  Guoan Zheng; Seung Ah Lee; Yaron Antebi; Michael B Elowitz; Changhuei Yang
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-03       Impact factor: 11.205

3.  A semi-automated neutral red based chemosensitivity assay for drug screening.

Authors:  P F Cavanaugh; P S Moskwa; W H Donish; P J Pera; D Richardson; A P Andrese
Journal:  Invest New Drugs       Date:  1990-11       Impact factor: 3.850

4.  PC12 cells differentiate into chromaffin cell-like phenotype in coculture with adrenal medullary endothelial cells.

Authors:  Y Mizrachi; J R Naranjo; B Z Levi; H B Pollard; P I Lelkes
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

5.  Cytotoxicity assays of new artificial tears containing 2-methacryloyloxyethyl phosphorylcholine polymer for ocular surface cells.

Authors:  Masahiko Ayaki; Atsuo Iwasawa; Yoshimi Niwano
Journal:  Jpn J Ophthalmol       Date:  2011-08-10       Impact factor: 2.447

6.  Assessment of cytotoxicity, genotoxicity and 7-ethoxyresorufin-O-deethylase (EROD) induction in sediment extracts from New Zealand urban estuaries.

Authors:  Patrick Heinrich; Lara L Petschick; Grant L Northcott; Louis A Tremblay; James M Ataria; Thomas Braunbeck
Journal:  Ecotoxicology       Date:  2017-01-12       Impact factor: 2.823

7.  In vitro lead-induced cell toxicity and cytoprotective activity of fetal calf serum in human fibroblasts.

Authors:  Carmen Dominguéz; Eduard Solé; Anna Fortuny
Journal:  Mol Cell Biochem       Date:  2002-08       Impact factor: 3.396

8.  Metallothionein induction in cultured fibroblasts and liver of a marine flatfish, the turbot,Scophthalmus maximus.

Authors:  S George; D Burgess; M Leaver; N Frerichs
Journal:  Fish Physiol Biochem       Date:  1992-05       Impact factor: 2.794

9.  Influence of zymosan (a non-specific macrophage stimulator) and of indomethacin on liver tumours--an experimental study in rats.

Authors:  S B Holmberg; P L Naredi; G O Lindnér; I H Karlberg; P L Daneryd; L M Karlsson; A Pettersson; U Stenram; L R Hafström
Journal:  J Cancer Res Clin Oncol       Date:  1995       Impact factor: 4.553

10.  Potent in vitro antifungal activities of naturally occurring acetylenic acids.

Authors:  Xing-Cong Li; Melissa R Jacob; Shabana I Khan; M Khalid Ashfaq; K Suresh Babu; Ameeta K Agarwal; Hala N Elsohly; Susan P Manly; Alice M Clark
Journal:  Antimicrob Agents Chemother       Date:  2008-05-05       Impact factor: 5.191
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