| Literature DB >> 3983646 |
M Schwartz, M Belkin, A Harel, A Solomon, V Lavie, M Hadani, I Rachailovich, C Stein-Izsak.
Abstract
Regeneration of fish optic nerve (representing regenerative central nervous system) was accompanied by increased activity of regeneration-triggering factors produced by nonneuronal cells. A graft of regenerating fish optic nerve, or a "wrap-around" implant containing medium conditioned by it, induced a response associated with regeneration in injured optic nerves of adult rabbits (representing a nonregenerative central nervous system). This response was manifested by an increase of general protein synthesis and of selective polypeptides in the retinas and by the ability of the retina to sprout in culture.Entities:
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Year: 1985 PMID： 3983646 DOI： 10.1126/science.3983646
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728