Literature DB >> 3981407

Determination of hydrazine in pharmaceuticals IV: Hydrazine and benzylhydrazine in isocarboxazid.

E G Lovering, F Matsui, D Robertson, N M Curran.   

Abstract

A GC procedure for the simultaneous determination of hydrazine and benzylhydrazine in isocarboxazid raw material and tablet formulations has been developed. The method is based on the reaction of benzoyltrifluoroacetone with hydrazine and benzylhydrazine to form the corresponding pyrazole derivatives. The minimum detectable amounts of hydrazine and benzylhydrazine in isocarboxazid are 0.002 and 0.02%, respectively.

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Year:  1985        PMID: 3981407     DOI: 10.1002/jps.2600740130

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  1 in total

1.  Quantification of Hydrazine in Human Urine by HPLC-MS-MS.

Authors:  Samantha L Isenberg; Melissa D Carter; Brian S Crow; Leigh Ann Graham; Darryl Johnson; Nick Beninato; Kandace Steele; Jerry D Thomas; Rudolph C Johnson
Journal:  J Anal Toxicol       Date:  2016-03-13       Impact factor: 3.367

  1 in total

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