Literature DB >> 3980275

Radiation-induced heart disease in rats.

S Lauk, Z Kiszel, J Buschmann, K R Trott.   

Abstract

After local irradiation of the rat heart with X ray doses of over 10 Gy (single dose), animals developed symptoms of radiation-induced heart disease, which at higher doses would lead to fatal cardiac failure. The LD 50 at 1 year was between 15 Gy and 20 Gy. The pericardium and epicardium responded to irradiation with exudative pericarditis after 4 months. Focal myocardial damage was secondary to progressive capillary damage.

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Year:  1985        PMID： 3980275     DOI： 10.1016/0360-3016(85)90314-1

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN： 0360-3016            Impact factor:   7.038


  42 in total

Review 1.  Experimental radiation-induced heart disease: past, present, and future.

Authors:  Marjan Boerma
Journal:  Radiat Res       Date:  2012-06-04       Impact factor: 2.841

Review 2.  Potential targets for intervention in radiation-induced heart disease.

Authors:  M Boerma; M Hauer-Jensen
Journal:  Curr Drug Targets       Date:  2010-11       Impact factor: 3.465

Review 3.  Radiation as a risk factor for cardiovascular disease.

Authors:  John E Baker; John E Moulder; John W Hopewell
Journal:  Antioxid Redox Signal       Date:  2011-03-23       Impact factor: 8.401

4.  PET/CT demonstrates increased myocardial FDG uptake following irradiation therapy.

Authors:  K Zöphel; C Hölzel; M Dawel; T Hölscher; C Evers; J Kotzerke
Journal:  Eur J Nucl Med Mol Imaging       Date:  2007-06-02       Impact factor: 9.236

5.  Evaluating Positron Emission Tomography-Based Functional Imaging Changes in the Heart After Chemo-Radiation for Patients With Lung Cancer.

Authors:  Yevgeniy Vinogradskiy; Quentin Diot; Bernard Jones; Richard Castillo; Edward Castillo; Jennifer Kwak; Daniel Bowles; Inga Grills; Nicholas Myziuk; Thomas Guerrero; Craig Stevens; Tracey Schefter; Laurie E Gaspar; Brian Kavanagh; Moyed Miften; Chad Rusthoven
Journal:  Int J Radiat Oncol Biol Phys       Date:  2020-01-23       Impact factor: 7.038

6.  p53 functions in endothelial cells to prevent radiation-induced myocardial injury in mice.

Authors:  Chang-Lung Lee; Everett J Moding; Kyle C Cuneo; Yifan Li; Julie M Sullivan; Lan Mao; Iman Washington; Laura B Jeffords; Rafaela C Rodrigues; Yan Ma; Shiva Das; Christopher D Kontos; Yongbaek Kim; Howard A Rockman; David G Kirsch
Journal:  Sci Signal       Date:  2012-07-24       Impact factor: 8.192

7.  Histological and physiological studies on rat heart following irradiation with single doses of X-rays.

Authors:  T K Yeung; J W Hopewell
Journal:  Br J Cancer Suppl       Date:  1986

8.  Assessing cardiac injury in mice with dual energy-microCT, 4D-microCT, and microSPECT imaging after partial heart irradiation.

Authors:  Chang-Lung Lee; Hooney Min; Nicholas Befera; Darin Clark; Yi Qi; Shiva Das; G Allan Johnson; Cristian T Badea; David G Kirsch
Journal:  Int J Radiat Oncol Biol Phys       Date:  2014-03-01       Impact factor: 7.038

9.  Role of p53 in regulating tissue response to radiation by mechanisms independent of apoptosis.

Authors:  Chang-Lung Lee; Jordan M Blum; David G Kirsch
Journal:  Transl Cancer Res       Date:  2013-10       Impact factor: 1.241

Review 10.  Myocardial diseases of animals.

Authors:  J F Van Vleet; V J Ferrans
Journal:  Am J Pathol       Date:  1986-07       Impact factor: 4.307
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