Literature DB >> 3979523

Intracellular accumulation of mercury in the anterior pituitary of rats exposed to mercuric chloride.

O Thorlacius-Ussing, B Møller-Madsen, G Danscher.   

Abstract

A histochemical technique has been used to reveal mercury deposits by light and electron microscopy in the anterior pituitary of adult rats. After administration of mercuric chloride either in the drinking water or by intraperitoneal injection, deposits were found within lysosomes and secretory granules in somatotrophs, thyrotrophs, follicular cells, and marginal cells. The amount of mercury deposited was proportional to the dose of mercuric chloride given. Significantly more mercury was found in rats given intraperitoneal injections compared to those intoxicated with mercuric chloride in the drinking water. Mercury was retained in the cells for at least 4 months after the last injection although the amount of deposits decreased in this period.

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Year:  1985        PMID： 3979523     DOI： 10.1016/0014-4800(85)90034-6

Source DB:  PubMed          Journal:  Exp Mol Pathol        ISSN： 0014-4800            Impact factor:   3.362


  7 in total

Review 1.  Long term persistence of mercury in the brain.

Authors:  J B Cavanagh
Journal:  Br J Ind Med       Date:  1988-10

2.  Normal pituitary hormone response to thyrotrophin and gonadotrophin releasing hormones in subjects exposed to elemental mercury vapour.

Authors:  E M Erfurth; A Schütz; A Nilsson; L Barregård; S Skerfving
Journal:  Br J Ind Med       Date:  1990-09

3.  Simultaneous ultrastructural demonstration of heavy metals (silver, mercury) and acid phosphatase.

Authors:  O Thorlacius-Ussing; P Møller Graabaek
Journal:  Histochem J       Date:  1986 Nov-Dec

4.  The endocrine disruptive effects of mercury.

Authors:  X Zhu; Y Kusaka; K Sato; Q Zhang
Journal:  Environ Health Prev Med       Date:  2000-01       Impact factor: 3.674

5.  Endocrine function in mercury exposed chloralkali workers.

Authors:  L Barregård; G Lindstedt; A Schütz; G Sällsten
Journal:  Occup Environ Med       Date:  1994-08       Impact factor: 4.402

6.  The concentration of twelve elements in the anterior pituitary from human subjects and rats as measured by particle induced X-ray emission (PIXE).

Authors:  O Thorlacius-Ussing; M Gregersen; N Hertel
Journal:  Biol Trace Elem Res       Date:  1988-08       Impact factor: 3.738

Review 7.  Methylmercury plus Ethanol Exposure: How Much Does This Combination Affect Emotionality?

Authors:  Diandra Araújo Luz; Sabrina de Carvalho Cartágenes; Cinthia Cristina Sousa de Menezes da Silveira; Bruno Gonçalves Pinheiro; Kissila Márvia Matias Machado Ferraro; Luanna de Melo Pereira Fernandes; Enéas Andrade Fontes-Júnior; Cristiane do Socorro Ferraz Maia
Journal:  Int J Mol Sci       Date:  2021-12-04       Impact factor: 5.923
  7 in total

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