Literature DB >> 3978068

Penetration of timolol eye drops into human aqueous humour: the first hour.

C I Phillips, R S Bartholomew, A M Levy, J Grove, R Vogel.   

Abstract

Samples of aqueous humour were removed from 26 eyes at the start of cataract extraction. Two drops of timolol 0.5% had been instilled into the conjunctival sac 12-71 minutes before operation. Analysis by gas chromatography showed a mean timolol concentration of 55.46 ng/mg, with a range of 8 to 100 ng/mg.

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Year:  1985        PMID： 3978068      PMCID： PMC1040566          DOI： 10.1136/bjo.69.3.217

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN： 0007-1161            Impact factor:   4.638


  6 in total

1.  Penetration of atenolol in the rabbit eye.

Authors:  F E Ros; H C Innemee; P A van Zwieten
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1978-11-30

2.  Penetration of timolol eye drops into human aqueous humour.

Authors:  C I Phillips; R S Bartholomew; G Kazi; C J Schmitt; R Vogel
Journal:  Br J Ophthalmol       Date:  1981-09       Impact factor: 4.638

3.  Penetration of timolol into the rabbit eye. Measurements after ocular instillation and intravenous injection.

Authors:  C J Schmitt; V J Lotti; J C LeDouarec
Journal:  Arch Ophthalmol       Date:  1980-03

4.  Electron-capture GLC determination of timolol in human plasma and urine.

Authors:  D J Tocco; F A deLuna; A E Duncan
Journal:  J Pharm Sci       Date:  1975-11       Impact factor: 3.534

5.  Penetration of five beta-adrenergic antagonists into the rabbit eye after ocular instillation.

Authors:  C Schmitt; V J Lotti; J C Le Douarec
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1981

6.  Ocular penetration of beta-adrenergic blocking agents. An experimental study with atenolol, metoprolol, timolol and propranolol.

Authors:  F E Ros; H C Innemee; P A van Zwieten
Journal:  Doc Ophthalmol       Date:  1980-04-15       Impact factor: 2.379
  6 in total
  4 in total

1.  Influence of the strength, drop size and viscosity of metipranolol eye drops on the concentration of the substance in human aqueous humour.

Authors:  C Kessler; H Bleckmann; G Kleintges
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1991       Impact factor: 3.117

2.  Influence of the concentration of metipranolol eye drops on the drug concentration in human aqueous humour.

Authors:  C Kessler; H Bleckmann; G Kleintges
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1991       Impact factor: 3.117

3.  Concentration of timolol in aqueous humour.

Authors:  L J Blanksma
Journal:  Doc Ophthalmol       Date:  1991       Impact factor: 2.379

4.  Penetration of nadolol into aqueous humour after a single oral dose.

Authors:  T H Tiong; S O Hung; M S Perelman
Journal:  Br J Clin Pharmacol       Date:  1988-07       Impact factor: 4.335
  4 in total

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