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Literature DB >> 3977647

Carbamazepine toxicity induced by concurrent erythromycin therapy.

E Carranco, J Kareus, S Co, V Peak, S Al-Rajeh.

Abstract

We describe a 41-year-old woman receiving carbamazepine for epilepsy, in whom concurrent erythromycin stearate administration led to carbamazepine toxicity, including inappropriate antidiuretic hormone syndrome. We review the literature on erythromycin-carbamazepine interaction and discuss the mechanism for such interaction.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1985 PMID： 3977647 DOI： 10.1001/archneur.1985.04060020105023

Source DB: PubMed Journal: Arch Neurol ISSN： 0003-9942

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Cited

11 in total

1. Acute drug prescribing to children on chronic antiepilepsy therapy and the potential for adverse drug interactions in primary care.

Authors: Philipp H Novak; Suzie Ekins-Daukes; Colin R Simpson; Robert M Milne; Peter Helms; James S McLay
Journal: Br J Clin Pharmacol Date: 2005-06 Impact factor: 4.335

2. Severe carbamazepine toxicity induced by concurrent erythromycin therapy.

Authors: C R Mota; C Carvalho; C Mota; P Ferreira; A Vilarinho; E Pereira
Journal: Eur J Pediatr Date: 1996-04 Impact factor: 3.183

3. Interactions Between Antiepileptic and Antibiotic Drugs: A Systematic Review and Meta-Analysis with Dosing Implications.

Authors: Carla Carnovale; Marco Pozzi; Faizan Mazhar; Giulia Mosini; Marta Gentili; Gabriëlla G A M Peeters; Emilio Clementi; Sonia Radice
Journal: Clin Pharmacokinet Date: 2019-07 Impact factor: 6.447

Carbamazepine toxicity induced by concurrent erythromycin therapy.

1. Acute drug prescribing to children on chronic antiepilepsy therapy and the potential for adverse drug interactions in primary care.

2. Severe carbamazepine toxicity induced by concurrent erythromycin therapy.

3. Interactions Between Antiepileptic and Antibiotic Drugs: A Systematic Review and Meta-Analysis with Dosing Implications.

Review 4. Drug interactions that matter. A critical reappraisal.

Review 5. Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.

Review 6. Macrolide antibacterials. Drug interactions of clinical significance.

7. Inhibition by erythromycin of the conversion of carbamazepine to its active 10,11-epoxide metabolite.

Review 8. Pharmacokinetic drug interactions of macrolides.

Review 9. Carbamazepine toxicity and poisoning. Incidence, clinical features and management.

Review 10. Pharmacokinetic aspects of treating infections in the intensive care unit: focus on drug interactions.