| Literature DB >> 3977116 |
R I Mazze, S A Rice, J M Baden.
Abstract
The MAC of halothane, isoflurane, and enflurane was determined using the tail-clamp technique in pregnant female, nonpregnant female, and male Swiss Webster mice (n = 216) and Sprague-Dawley rats (n = 112). Mean MAC values (+/-SD) for halothane, isoflurane, and enflurane in mice were 0.95 +/- 0.07%, 1.34 +/- 0.10%, and 1.95 +/- 0.16%, respectively; values in rats were 1.03 +/- 0.04%, 1.46 +/- 0.06%, and 2.21 +/- 0.08%, respectively, all significantly higher than in mice. Neither the sex of the animals nor whether female animals were pregnant influenced the results.Entities:
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Year: 1985 PMID： 3977116 DOI： 10.1097/00000542-198503000-00021
Source DB: PubMed Journal: Anesthesiology ISSN： 0003-3022 Impact factor: 7.892